Kath Lavidge '74, P '09 - Chair. Q4 2016 saw a stake doubling at prices between ~$28 and ~$36. This is one of the funds highest conviction picks, as Baker Bros still owns nearly 26% of the companys shares, which have been held since 2010. Shares started trading at ~$24 and currently goes for ~$246. Recession Risk Determine whether Baker Brothers Life Sciences grew or shrank during the last recession. For the Baker Bros. -- the biggest shareholder in both companies -- the value of its investments have soared by about $1.4 billion. This Agreement may be executed in any number of counterparts (including by facsimile or Julian Baker and Felix Baker 's Baker Bros. Advisors recently filed an amended Form 13D with the SEC to report the sale of common shares of Biocryst Pharmaceuticals Inc (NASDAQ: BCRX). value remained steady this quarter at $22.77B. Shares started trading at ~$10 and currently goes for $85.56. Blue Sky Digital Outdoor Advertising Fund Fund Data, Sarasin Ie Global Equity Opportunities (Usd) Fund Data, Themelios Ventures Ii-A, L.P. Fund Data. Si vous y consentez, nous et nos partenaires utiliserons galement des cookies et autres traceurs de mesure daudience, de publicit et de rseaux sociaux, dont le dtail des finalits est accessible depuis le bouton Grer les paramtres . They have a ~29% ownership stake in the business. Companys Amended and Restated Certificate of Incorporation as in effect on the date hereof). Baker Brothers, a biotech investment firm, was founded by Julian & Felix Baker in 2000. I am not receiving compensation for it (other than from Seeking Alpha). The position was held stable during the quarter. For more information, please see the SECs Web Site Privacy and Security Policy. recommended to the Companys stockholders for election as directors of the Company at each annual or special meeting of the Companys stockholders at which directors are to be elected (an Election Meeting),one Council Members. Notices must be given: (a)by personal delivery, with receipt acknowledged; (b)by email followed by hard copy delivered by the methods The funds philosophy stands in holding its investments ordinarily for three years, though its higher-conviction investments can be seen held for longer. According to Crain's Chicago Business, some of Chicago's fledgling biotech companies such as Xeris Pharmaceuticals and Evanston-based Aptinyx went public in 2018 alongside other local life sciences startups an indication of investors' mounting interest in the city's biotech scene. [Remainder of page intentionally left blank]. This Agreement, the Bylaws and The fund has grown rapidly over the years due to its extraordinary returns and currently boasts approximately $15.2 billion of assets under management (AUM). Form D contains basic information about the offering and the company. All rights reserved. The increase happened at ~$72 per share. The two brothers are still at the helm of the fund, and along with around 25 employees, cater to 2 clients. individual as a nominee to the Board of Directors if a majority of the disinterested members of the Board of Directors reasonably and in good faith determines, after consultation with the Companys outside legal counsel and upon written advice We also use third-party cookies that help us analyze and understand how you use this website. Click to reveal Please disable your ad-blocker and refresh. Nous utilisons des cookies techniques ncessaires au bon fonctionnement du site internet. The funds strategy includes utilizing a fundamentally-driven way of investing to come up with its investment decisions, also known as bottom-up investing. We're built to manage the complete launch and commercialization of products or address specific program or patient needs. the Investor and its Affiliates, collectively, no longer beneficially own the Required Shares, (ii)the third (3rd) anniversary of the closing of the IPO, and (iii)the consummation of a Deemed Liquidation Event (as defined in the The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". The stock currently trades at $23.62. breach or default, or an acquiescence therein, or of or in any similar breach or default thereunder occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other breach or default therefore or thereafter occurring. As a percentage of AUM, allocation to the highest conviction picks can be very high at over 30%. Baker Brothers 13F portfolio value remained almost steady at $22.77B this quarter. The Baker Brothers Entities nominated Fuchs as one of eight nominees to the board of directors at AnorMED, Inc. and, it can be inferred, given the timing, that Fuchs was also appointed by the Baker Brothers Entities to the Mirati You can also sign up for email updates on the SEC open data program, including best practices that make it more efficient to download data, and SEC.gov enhancements that may impact scripted downloading processes. Necessary cookies are absolutely essential for the website to function properly. The filing was for a pooled investment fund: other investment fund The notice included securities offered of Pooled Investment Fund Interests. The fund is located in New York, New York and will invest in United States. Pour plus dinformations, veuillez consulter notre politique de gestion des cookies. (1)person designated at any time and from time to time by the Investor (the Investor Designee); provided that, the Company shall have no obligation to support the nomination of or cause the Board of Directors to include in Employees: 2,680 21823 30TH DRIVE SE, SUITE, BOTHELL, WA, 98021 4255274000 seagen.com Seagen Inc. develops and commercializes therapies for the treatment of cancer in the United States and internationally. Despite a losing win-record, the firm has managed to post outstanding returns through prudent position sizing. All remedies, either under this Agreement, or by law or otherwise afforded to any party, shall be cumulative and not alternative. Since then the activity has been minor. The company offers drugs for the treatment of patients with Hodgkin lymphoma, advanced or metastatic urothelial cancer, and unresectable or metastatic HER2-positive breast cancer, amongst others. The life sciences sector is changing by the minute. In . This SEC practice is designed to limit excessive automated searches on SEC.gov and is not intended or expected to impact individuals browsing the SEC.gov website. In the event that the Investor Designee resigns from his or her seat on the Board of Directors or is Companys shares are listed, the Bylaws or any policy, or guidelines previously approved by the Board of Directors, provided that a direct or indirect purpose of any such policy or guideline is not to obstruct the Investors right to validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. BAKER BROTHERS LIFE SCIENCES, L.P. By: BAKER BROS. ADVISORS LP, management company and investment adviser to Baker Brothers Life Sciences, L.P., pursuant to authority granted to it by Baker Brothers Life Sciences Capital, L.P., general partner to Baker Brothers Life Sciences, L.P., and not as the general partner. Its flagship products include JAKAFI, which is a drug for the treatment of myelofibrosis and polycythemia, and Iclusig, a kinase inhibitor to treat chronic myeloid leukemia. Farah Champsi MBA '85. The stake goes back to funding rounds prior to their IPO last September. Its stake in Seattle Genetics is up $1 billion since news of. Note: Regulatory filings since the quarter ended show them owning ~33.8M shares of Incyte. As Chicago's biotech ecosystem continues to expand . Baker Bros. Advisors LP 860 Washington Street, 3 rd Floor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) October 11, 2019 (Date of event which requires filing of this statement) Julian has a business background from Harvard, while Felix has a Ph.D. in Immunology from Stanford. Additionally, the rights set forth in this Section2(c) may of the Election Meeting and the term of such Investor Designee as a director on the Board of Directors does not expire at such Election Meeting. This cookie is set by GDPR Cookie Consent plugin. The firm primarily invests in life science companies. Last two quarters have seen minor increases. Note: Baker Brothers controls ~10% of Madrigal Sciences. The current estimated net worth of Kodiak Sciences Inc's Director, Felix Baker, is estimated to be about $16.52B . Shares started trading at ~$33 and currently goes for $11.43. (c)Subject at all times to Section3(n) below and the other limitations set forth in this See how we calculate 13F filing performance here, Baker Brothers Portfolio & 4 Largest Public-Equity Investments, 20 Highest Yielding Monthly Dividend Stocks. subject to the conditions set forth herein. Management owns 12 percent of the fund. Form D is a form to be used to file a notice of an exempt offering of securities with the Securities and Exchange Commission. in Molecular and Cell Biology from The Pennsylvania State University, and a Masters in both Biotechnology and Business Administration from the University of Pennsylvania. BeiGene is an early commercial-stage biopharmaceutical firm working on developing and commercializing innovative molecularly-targeted and immune-oncology drugs for the treatment of cancer. Madrigal Pharmaceuticals (MDGL) and Mirati Therapeutics (MRTX): These two small (less than ~1.10% of the portfolio each) stakes were kept steady this quarter. This is crucial when investing in the biotech industry, as each company is very unique, requiring niche knowledge to understand its business model. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. As a percentage of AUM, allocation to the highest conviction picks can be very high at over 30%. 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